Nfl Favorites To Win Super Bowl 2025. Leading the odds are the two conference champions that faced off in the super bowl earlier. The chiefs and the lions now both sit at +400 to hoist the lombardi trophy at the end of the season.

Preseason favorites the kansas city chiefs (+375) are once again being given the shortest odds to win the lombardi trophy in february after a week 16 win over the houston. Leading the odds are the two conference champions that faced off in the super bowl earlier.